Diffuse skin hyperpigmentation associated with chronic minocycline use in a patient with prosthetic joint infection
نویسندگان
چکیده
Cutaneous hyperpigmentation is a recognized adverse effect of chronic minocycline use occurring in up to 50% of patients. In this report we present a rare case of extensive skin hyperpigmentation involving both lower extremities in a patient receiving long term minocycline. The patient was receiving minocycline as suppression for chronic prosthetic joint infection. Risk factors associated with minocycline-induced cutaneous pigmentation (MICH) will be reviewed.
منابع مشابه
706Minocycline-Induced Cutaneous Hyperpigmentation in an Orthopedic Patient Population
Background. Patients on chronic minocycline suppression for orthopedic infections at a single institution were studied for development of minocycline-induced cutaneous hyperpigmentation and analysis of risk factors. Methods. This is a retrospective cohort study of Mayo Clinic patients with hardware or non-hardware associated chronic orthopedic infections treated with long termminocycline suppre...
متن کاملCongenital diffuse Melanosis in a father and two sons
Congenital diffuse Melanosis is one of the rarest clinical manifestations of hereditary universal Melanosis and only few cases have been reported all over the world. The presented case is a 54-year-old man who presented to us complaining of erythematous annular lesions on his face and neck since 8 months ago. Diffuse pigmentation of his skin took our attention. According to the patient, d...
متن کاملMinocycline-induced hyperpigmentation: comparison of 3 Q-switched lasers to reverse its effects
Minocycline is a tetracycline derivative antibiotic commonly prescribed for acne, rosacea, and other inflammatory skin disorders. Minocycline turns black when oxidized, leading to discoloration of the skin, nails, bulbar conjunctiva, oral mucosa, teeth, bones, and thyroid gland. Hyperpigmentation has been reported after long-term minocycline therapy with at least 100 mg/day. Three types of mino...
متن کاملMinocycline-induced hyperpigmentation in patients with pemphigus and pemphigoid.
BACKGROUND Immunosuppressive medications typically used to treat the immunobullous disorders pemphigus vulgaris, pemphigus foliaceous, and bullous pemphigoid can have serious adverse effects. The tetracycline family of antibiotic drugs has been shown to be effective in the treatment of these conditions with a more favorable side effect profile. Minocycline hydrochloride use has been associated ...
متن کاملMinocycline-Induced Cutaneous Hyperpigmentation in an Orthopedic Patient Population
Background. The objectives of this study were to estimate the incidence and evaluate risk factors for development of minocycline-induced cutaneous hyperpigmentation in patients with orthopedic infections. Methods. Patients with orthopedic infections evaluated at Mayo Clinic (Rochester, MN) and treated with minocycline from 1 January 2002 to 31 December 2011 were retrospectively identified. Lo...
متن کامل